Infertility, like every other medical condition, makes no distinction between the financial statuses of patients when it strikes. This implies that there will be people who can afford expensive medical treatments for infertility and there will be others who cannot. For this reason, medical science and research has been making efforts to devise medical procedures which are affordable, yet effective.

As the name suggests, mini IVF, also referred to as minimal stimulation IVF, is a less expensive and less aggressive alternative to the conventional In Vitro Fertilization. The procedure is very similar to IVF in many ways, except the fact that it makes use of low dose of ovarian stimulation medication so that only a few eggs are produced by the ovaries.

All about Mini IVF

Mini IVF is a simpler version of IVF, during which the focus is on quality of eggs rather than their number. Conventional IVF strives at churning out a large number of eggs from the ovaries by administering massive hormonal doses during the ovarian stimulation; mini IVF, on the other hand, takes a gentler and holistic approach to achieve conception with fewer, but better quality eggs.

An ingeniously simple protocol is used for making this technique a success, enabling even older ovaries to bring out healthy and viable eggs. It is important to understand that only 3 to 5 eggs of good quality are sufficient to yield a healthy pregnancy, which is the reason why mini IVF is seen as a feasible medical technique to counter infertility.

Conventional IVF procedure uses high dose of hormones and brings out numerous eggs, out of which only a few are good enough to turn out into viable embryos. Conversely, mini IVF is carried out with daily dosage of Clomid pills, instead of gonadotropins used in IVF (although low doses of gonadotropins may also be used for stimulating the ovaries to yield only a few eggs). In some cases, specialists even rely on natural cycle, with no stimulation drugs being used for the mini IVF.

Mini IVF is not suitable for all, but can rather be manifested as a tailor-made treatment option for a selected group of patients struggling with infertility. For instance, it is advisable for older women and/or those with poor ovarian reserve to opt for this approach, because they may not be able to produce too many healthy eggs with more aggressive treatment as well. The reason is that such patients do not simple respond too well to ovarian stimulation drugs. So it would be no use to go for expensive treatment and heavy medication if the end results are going to be relatively similar.

Pros and Cons of Mini IVF

Mini IVF has a series of advantages and disadvantages over conventional IVF and both of these have to be considered to shortlist it as the best way out for individual cases.

The Pros:

  • Since the use of drugs and hormonal medications is reduced to the minimum in this procedure, there are fewer side effects and complications such as ovarian hyperstimulation and hormonal swings. This makes mini IVF a preferable option for women who are at a higher risk of Ovarian Hyperstimulation Syndrome (OHSS)
  • The chances of multiple pregnancies are almost nil as generally only a single embryo is transferred in mini IVF
  • The cost of the procedure is much lesser than that of conventional IVF and fewer, better quality eggs are produced, the surplus amongst which can be frozen for later use

The Cons

  • Since the number of eggs produced in mini IVF is fewer, there are chances that none may reach the embryo stage in the lab and the entire cycle may be lost
  • In case the mini IVF cycle fails, there are chances that the patient may not have any surplus embryos left for freezing for further use as there are already very few of them in number
  • Though the cost of the procedure is lower than that of typical IVF, a lower success rate may actually elevate the effective cost as the number of attempts required for a successful pregnancy may be more as compared to conventional IVF

Overall, the effectiveness of mini IVF is yet to be established because its success rate is still under research. At the same time, studies have pointed to the fact that the success rate of conventional IVF is considerably higher as compared to mini IVF, though the risks of complications such as OHSS and multiple pregnancies has been muck lower. Moreover, cost is seen as a major factor influencing the decision of the patients in this regard. Mini IVF is a procedure which is not just for everyone and its suitability is to be considered with an individualistic approach, which also has to be a more realistic one, both for the patients as well as the doctor.

Gaudium IVF is a trusted infertility clinic which follows a tailor-made approach for each of its patient, so that the chances of success of the treatment are maximized. Visit for a free second opinion by the leading fertility specialist, Dr Manika Khanna.